I frequently find myself launching the macrobuttons app only to find that it is invisible. Sometimes, I can right-click the tray icon and select "Show macro buttons (default position) but often that does not work, either. The only real reliable method I have, is to shift+rightclick the taskbar icon, select maximise, then use windows snap to allow me to resize from the maximised window.
I suspect this is related to my multi-monitor setup. I often find this happening after I have enabled or disabled a monitor. Perhaps it is worth mentioning, that I mostly use my secondary monitor, and have my primary monitor disabled - so it's possible that this is a problem because the 'first' monitor disappears? I don't know....
Anyway as I said it's not a big problem, but still, perhaps it's one that's not too hard to fix