This is my current setup:



From the examples above I have anything that plays music and from browsers go through CABLE-A, any 3rd party software that gives out sound alerts goes through CABLE-B, VOIP programs such as Discord goes through CABLE, and everything else goes through the default. I also use OBS for streaming so anything I want piped to OBS I just switch on B2 in VoiceMeeter and if friends wants to hear something I'm listening to when chatting in Discord I switch on B1.
This should work as it is, right?
Also today I noticed that Windows somehow set all my audio cables to muted and left me scratching my head for 3 hours wondering why no sound was coming through them in VoiceMeeter.